1. The complement system is controlled by cells that secrete neutralizing proteins. 2. In the complement system low C3 levels are associated with systemic lupus erythematosus 3. If this occurs, an immune response mediated by the complement system will occur. 4. Also, C4 and C2 cleavage goes unchecked, resulting in auto-activation of the complement system . 5. These mechanisms include antimicrobial peptides called defensins, pattern recognition receptors, and the complement system . 6. Nonetheless, it is known that XNAs and the complement system are not primarily involved. 7. IgA does not usually activate the complement system and is not involved with phagocytosis. 8. Other basic immune mechanisms, including phagocytosis and the complement system , evolved in ancient eukaryotes. 9. The M-protein aids in immune evasion by inhibiting phagocytosis and inactivating the complement system . 10. Microbes may activate the complement system directly and complement component C3b bind to microbes.
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